FDA-Approved Therapy for Treatment-Resistant Depression

At Quad Cities Ketamine & Wellness Clinic, we provide both IV ketamine therapy and Spravato® (esketamine), the only FDA-approved ketamine-based nasal spray for treatment-resistant depression.

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What is Spravato®?

Spravato® is a prescription nasal spray, derived from ketamine, designed for adults with depression that hasn’t improved with traditional medications. It is taken in a clinical setting under medical supervision, alongside your existing oral antidepressant.

How Spravato® Works

  • Targets the NMDA receptor in the brain
  • Helps restore balance in glutamate pathways
  • May reduce symptoms of depression, including low mood and loss of interest
  • Often works where other medications have not

What to Expect During Treatment

  • Spravato® is self-administered in our clinic under direct supervision
  • Sessions last about 2 hours for monitoring and safety
  • Most patients receive treatment twice weekly for the first month, then taper based on their response
  • You will need a safe ride home after each session

Is Spravato® Right for You?

Spravato® may be an option if you have:

  • Major depressive disorder (MDD)
  • Tried two or more antidepressants without success
  • Symptoms that interfere with daily life

Our team will perform a thorough consultation to determine whether Spravato® or IV ketamine is the best fit for your needs.

Why Choose Quad Cities Ketamine & Wellness?

  • Experienced Team –  Iowa’s longest running ketamine clinic.
  • Dual Options – IV ketamine & FDA-approved Spravato®
  • Expert Providers – CRNA & DNP-FNP overseeing all care
  • Personalized Plans – Tailored treatment for your needs
  • Comfortable Setting – Private, supportive environment
  • Whole-Person Care – Infusion + wellness therapies
  • Insurance Accepted – Affordable care
  • Convenient Location – Serving the Quad Cities area, located centrally between Bettendorf and Davenport, Iowa.
  • Evidence-Based – Research-driven protocols
  • Ongoing Support – Follow-up and progress tracking

Next Steps

Don’t wait to explore your options. Our team is here to guide you toward relief and renewed hope.

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